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© 2003 by CRC Press LLC Opioid Dependence and Knockout Mice 7 7 NK1 Analgesia unchanged; hyperlocomotion abolished CPP abolished Jump abolished; other 41 somatic signs unchanged; withdrawal CPA reduced GluR-A and GluR-A(RR)b Analgesia unchanged; hyperlocomotion unchanged Abolished in GluR-A; unchanged in GluR- A(RR) (TF) Context- independent sensitization abolished Somatic signs reduced in 42 GluR-A, unchanged in GluR-A(RR)) OFQN ORL-1 Analgesia unchanged Unchanged (TI) Jump increased 43 44 αCGRP IL6 Analgesia reduced; SIA abolished Unchanged (TF) Faster (HP) Heroin SA unchanged Somatic sitee reduced 46 Analgesia unchanged Analgesia unchanged Reduced (TP) Reduced (TP and TF) Jump reduced; other 45 somatic signs abolished Analgesia Fotex 47 SIA abolished aCPA, conditioned place aversion; CPP, conditioned place preference; DA, dopamine; HP, hot plate; Nuc Acc, nucleus accumbens; SA, self-administration; SIA, stress-induced analgesia; TF, Foex flick; TI, tail immersion; TP, tail pinch.
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