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See also peroxidases orally administered drug and metabolic transformation in, 19 organophosphate poisoning, 14 organophosphates 14, 124 oxazole ring, 9 oxene, 36, 76, 9294, 97 oxene hydrogen atom abstraction, 37 oxidation pathways, 67101 oxidative decarboxylation, 96 oxidative dehydrogenation, 86, 88, 157 oxidative N-dalkylation, 76 oxidative pathways and enzymes mediating them, 33 oxidative reactions catalyzed by XOR, 64 oxidized glutathione (GSSG), 117, 118 oxygen atom transfer mechanism of, 36 oxygen rebound step, 38 P450 enzymes catalytic cycle, 35 cloned human, 26 in liver and ER, 33 membrane-bound enzymes, 35 nomenclature, 41 substrate oxidation at various sites, 37 PAPS, see 3-phosphoadenosine 5-phosphosulfate P450-catalyzed hydrogen atom abstraction complexeties of, 68 P450-catalyzed metabolic pathways, 25 P450-catalyzed oxidation, 29, 37, 38, 40, 75, 84, 86, 89, 95, 97 paraoxon, structure of, 125 paraoxonase (PON1), 122, 124 paraquat.
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