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; US Patent 3,562,258; Feb. Insertion of the CS5 domain causes some perturbation of the LCST, but the objective of depressing the transition to below room temperature has been met for both of these materials. For patients who do not respond, oral prednisolone may be given. Regulation of Glucose Concentrations in the Fasted State The contribution of gluconeogenesis becomes progressively more important as the duration of fast is extended and hepatic glycogen stores are depleted.
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